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Image Search Results
Journal: Research Square
Article Title: Alcohol and e-cigarette damage alveolar-epithelial barrier by activation of P2X7r and provoke brain endothelial injury via extracellular vesicles
doi: 10.21203/rs.3.rs-3552555/v1
Figure Lengend Snippet: ETH, ALD, and e-Cig (1.8% nicotine) exposure increased the size and numbers of shed lung epithelial EVs, and P2X7r inhibition brought them to control levels. (A) Overnight stimulation of hPAEpiC with ETH, ALD, and e-Cig (1.8% nicotine)-conditioned media increased the EV particle size by 20–30%. The EV number was increased by 2-fold after ETH exposure and 3-fold after ALD or e-Cig (1.8% nicotine) exposure. In contrast, A80 pretreatment decreased the size and number of EVs. Data is presented as mode ± standard error) (n = 3).
Article Snippet: ETH 200 Proof, 99.5% pure aldehyde (ALD), and
Techniques: Inhibition, Control, Concentration Assay